Welcome to 5299 Burke Lane, a one-of-a-kind private retreat set on 2.67 wooded acres in the heart of Dewitt. Elevated atop a quiet hill on a dead-end street, with neighborhoods stretching below, this architecturally stunning contemporary offers exceptional privacy without sacrificing convenience. Located minutes from JD schools, shopping, dining, hospitals, universities, and major highways. Downtown Syracuse is only 10 minutes away, the airport just 15, and NYC about 4.5 hours- blending retreat and accessibility. Facing east, the home greets each morning with vibrant sunrises, while the interior is transformed daily by moving light. Vaulted ceilings, a dramatic spiral staircase, and expansive walls of glass create an indoor-outdoor connection and highlight the home's mid-century design. The kitchen features handcrafted Wood-Mode cabinetry, stainless steel appliances, a curved breakfast bar, and a bright dining space. The main level also includes a versatile bedroom, cozy family room with hardwoods and a striking stone fireplace, den/home office, powder room, and laundry center. Two wood-burning fireplaces create warmth and ambiance throughout the seasons. Upstairs, the private primary suite features an en-suite bath and walk-in closet. Two additional bedrooms share another full bath. The walkout lower level offers even more flexibility. There you’ll find a cedar-lined rec room, bonus room for fitness or guests, a full bath, and a charming wine cellar. The activity room—practically soundproof—features a gas fireplace and offers an ideal space for music lovers, whether listening or playing. The layout makes entertaining effortless, whether hosting a crowd or enjoying quiet conversation. Outside, an expansive multi-level deck offers wooded views. Wildlife is abundant—deer, foxes, hawks, owls, chipmunks, & birds including cardinals, blue jays, goldfinches, and hummingbirds. Each spring, a rare & fragrant stand of pink lilies-of-the-valley blooms for weeks. The neighborhood is beloved by walkers & nature lovers alike. With supreme privacy and a low-maintenance natural landscape, this home is an inspiring retreat full of style, soul, & serenity. SHOWINGS START 4/25.